PDBbind database v2011 is released

• 关键字: PDBbind database v2011 released 发布者：宣传部 发布时间：2011-09-26 09:23:04 点击数: 7834次

Dear researchers,
 
We announce another release of the PDBbind database, i.e. version 2011. The PDBbind database aims at providing a comprehensive collection of experimentally measured binding affinity data for all biomolecular complexes deposited in the Protein Data Bank. The PDBbind database was first released to the public in 2004 by Prof. Shaomeng Wang's group at the University of Michigan. It is now maintained and further developed by Prof. Renxiao Wang's group at the Shanghai Institute of Organic Chemistry. The PDBbind database is updated annually to keep up with the growth of the Protein Data Bank.
 
This release, i.e. version 2011, provides binding affinity data for a total of 7,986 biomolecular complexes in PDB, including protein-ligand (6,051), nucleic acid-ligand (66), protein-nucleic acid (428), and protein-protein complexes (1,441), which is the largest collection of this kind so far. All binding data were carefully curated from original references rather than assembled from other data resources. Binding affinity data included in this release have increased by ~20% as compared to the last release (version 2010). Besides binding affinity data, "clean" processed structural files of the protein-ligand complexes in PDBbind are also provided for download.
 
The PDBbind version 2011 is available on the PDBbind-CN web server at http://www.pdbbind-cn.org/. The basic information of each complex in PDBbind is accessible without the need of registration. Registration is required only if the users want to use the displaying and searching services provided on this web site or to download the data in PDBbind. Registration is free of charge for all academic and commercial/industrial users. More than 1,600 users from over 40 countries have already registered to use this database, and this number is still growing.
 
We love to receive your comments on the PDBbind database so that we can improve it further.
 
Best regards,
 
Prof. Renxiao Wang & the whole PDBbind team
Shanghai Institute of Organic Chemistry
Chinese Academy of Sciences
Shanghai, P. R. China